生物活性

• 描述Risperidone hydrochloride is a serotonin 5-HT2 receptor blocker (Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist (Ki= 1.4 nM).
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT02374567	Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse <<	Phase 3	Terminated	-	Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse <<
  NCT01765829	Psychosis Nos/Other	Phase 3	Unknown	November 2015	Spain ... more >> Mental Health Unit Villamartín Recruiting Villamartín, Cádiz, Spain, 11650 Contact: José María Mongil San Juan, MD    0034956040209    cheman45@gmail.com    Principal Investigator: José María Mongil San Juan, MD          Mental Health Unit Baza Recruiting Baza, Granada, Spain, 18800 Contact: Eva Bravo Barba, MD       eva.bravo.barba@gmail.com    Principal Investigator: Eva Bravo Barba, MD          Mental Health Unit Motril Recruiting Motril, Granada, Spain, 18600 Contact: María Luisa Barrigón Estévez, MD    0034958038849    marial.barrigon.sspa@juntadeandalucia.es    Principal Investigator: María Luisa Barrigón Estévez, MD          Mental Health Unit Andújar Recruiting Andújar, Jaén, Spain, 23740 Contact: Fernando Sarramea Crespo, MD, PhD    0034953021717    fernandosarramea@hotmail.com    Principal Investigator: Farnando Sarramea Crespo, MD, PhD          Mental Health Unit Martos Recruiting Martos, Jaén, Spain, 23600 Contact: Miguel Ortigosa Luque, MD       migueortigosa@hotmail.com    Principal Investigator: Miguel Ortigosa Luque, MD          Mental Health Unit Miraflores Not yet recruiting Alcobendas, Madrid, Spain, 28100 Contact: María Luisa Zamarro Arraz, MD, PhD    0034916530108    zamarroluisa@yahoo.es    Principal Investigator: María Luisa Zamarro Arraz, MD, PhD          Hospital Infanta Sofía Not yet recruiting San Sebastian de los Reyes, Madrid, Spain, 28702 Contact: María Rosario Gutiérrez Labrador, MD       rosagutierrez@psiquiatra.e.telefonica.net    Principal Investigator: María Rosario Guitiérrez Labrador, MD          Mental Health Unit Valle del Guadalhorce Not yet recruiting Cártama, Málaga, Spain, 29580 Contact: Daniel Gutiérrez Castillo, MD    0034951033931    dgutierrezcastillo@gmail.com    Principal Investigator: Daniel Gutiérrez Castillo, MD          Mental Health Unit Las Lagunas Not yet recruiting Fuengiróla, Málaga, Spain, 29650 Contact: María Isabel Osuna Carmona, MD       maribelosunac@hotmail.com    Principal Investigator: María Isabel Osuna Carmona, MD          Fundación Argibide Not yet recruiting Pamplona, Navarra, Spain, 31007 Contact: Ignacio Mata Pastor, MD, PhD    0034948266650    nacho.mata70@gmail.com    Principal Investigator: Ignacio Mata Pastor, MD, PhD          Hospital El Tomillar Recruiting Dos Hermanas, Seville, Spain, 41700 Contact: Joaquín Carlos Martín Muñoz, MD, PhD    0034955016083    joaquinmartin@hotmail.com    Principal Investigator: Joaquín Carlos Martín Muñoz, MD, PhD          Hospital Francesc de Borja Recruiting Gandía, Valencia, Spain, 46700 Contact: María Lacruz Silvestre, MD, PhD       maria.lacruz.silvestre@gmail.com    Principal Investigator: María Lacruz Silvestre, MD, PhD          Hospital de Basurto Not yet recruiting Bilbao, Spain, 48013 Contact: Sonia Bustamante Madariaga, MD, Phd    0034944 006137    sonia.bustamantemadariaga@osakidetza.net    Principal Investigator: Sonia Bustamante Madariaga, MD, PhD          Mental Health Unit Tetuán Not yet recruiting Madrid, Spain, 28003 Contact: Mariano Hernández Monsalve, MD, PhD    0034915347363    hergoico@gmail.com    Contact: Ruth Berdún Pe, MD       ruthberdun@yahoo.es    Principal Investigator: Mariano Hernández Monsalve, MD, PhD          Lafora Hospital Not yet recruiting Madrid, Spain, 28049 Contact: Juan Dios Molina Martín, MD, PhD       jmolinamar@hotmail.com    Principal Investigator: Juan Dios Molina Martín, MD, PhD          Hospital Carlos Haya Recruiting Málaga, Spain, 29009 Contact: Fermín Mayoral Cleríes, Md, PhD       fermin.mayoral.sspa@juntadeandalucia.es    Principal Investigator: Fermín Mayoral Cleríes, MD, PhD          Virgen del Rocío Hospital Recruiting Seville, Spain, 41013 Contact: Clara M. Rosso Fernández, MD    0034955013414    claram.rosso.sspa@juntadeandalucia.es    Contact: Miguel Ruiz Veguilla, MD, PhD    0034955013414    mruizveguilla@yahoo.com    Principal Investigator: Miguel Ruiz Veguilla, MD, PhD Collapse <<
  NCT03557931	Schizophrenia	Phase 2	Recruiting	December 2019	United States, Arkansas ... more >> Woodland Research Northwest, LLC Recruiting Rogers, Arkansas, United States, 72758 United States, California CNS Research Science, Inc. Recruiting Cerritos, California, United States, 90703 Collaborative Neuroscience Network, LLC Recruiting Garden Grove, California, United States, 92845 Synergy East Recruiting Lemon Grove, California, United States, 91945 Pacific Research Partners, LLC Recruiting Oakland, California, United States, 94607 California Neuropsychopharmacology Clinical Research Institute-LA, LLC Recruiting Pico Rivera, California, United States, 90660 Artemis Institute for Clinical Research Recruiting San Diego, California, United States, 92103 Sharp Mesa Vista Hospital Recruiting San Diego, California, United States, 92123 Collaborative Neuroscience Network, LLC Recruiting Torrance, California, United States, 90502 United States, Georgia Radiant Research, Inc. Recruiting Atlanta, Georgia, United States, 30328 Atlanta Center for Medical Research Recruiting Atlanta, Georgia, United States, 30331 United States, Illinois Alam Medical Research Inc. Recruiting Chicago, Illinois, United States, 60612 Uptown Research Institute Recruiting Chicago, Illinois, United States, 60640 United States, Michigan Michigan Clinical Research Institute PC Recruiting Ann Arbor, Michigan, United States, 48105 Cherry Street Services, Inc. Recruiting Grand Rapids, Michigan, United States, 49503 United States, New Jersey Hassman Research Institute Recruiting Berlin, New Jersey, United States, 08009 United States, New Mexico Albuquerque Neuroscience Inc. Recruiting Albuquerque, New Mexico, United States, 87109 United States, New York SPRI Clinical Trials, LLC Recruiting Brooklyn, New York, United States, 11235 CNS Research Science, Inc. Recruiting Jamaica, New York, United States, 11432 Manhattan Psychiatric Center's 125th Street Clinic Recruiting New York, New York, United States, 10035 United States, Ohio Midwest Clinical Research Center Recruiting Dayton, Ohio, United States, 45417 United States, Texas InSite Clinical Research, LLC Recruiting DeSoto, Texas, United States, 75115 Pillar Clinical Research, LLC Recruiting Garland, Texas, United States, 75042 Pillar Clinical Research, LLC Recruiting Richardson, Texas, United States, 75080 Collapse <<

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• 参考文献

• [1] Bardgett ME, Franks-Henry JM, et al. Adult rats treated with risperidone during development are hyperactive. Exp Clin Psychopharmacol. 2013 Jun;21(3):259-67.

  [2] Chen ML, Tsai TC, et al. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int Immunopharmacol. 2012 Jan;12(1):197-204.